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SLU-PP-332 CAS - 303760-60-3

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SLU-PP-332 CAS: 303760-60-3 | Molecular formula: C18H14N2O2 | Molecular weight: 290.3 g/mol.

Product information

SLU-PP-332 – CAS 303760-60-3

SLU-PP-332 is supplied by Rexar as a research-grade chemical reference material for analytical chemistry, compound identification and comparative laboratory workflows. Chemically identified as 4-hydroxy-N'-[(E)-naphthalen-2-ylmethylidene]benzohydrazide, SLU-PP-332 combines a substituted benzohydrazide region, a phenolic hydroxyl group, an azomethine linkage and an extended naphthalene aromatic system. The material is supplied exclusively for controlled research environments requiring verified chemical identity, consistent structural documentation and reproducible analytical comparison.

Research-grade material distributed by Rexar within the European Union.

SLU-PP-332 (CAS 303760-60-3) is supplied in sealed laboratory packaging to support traceability, storage integrity and laboratory handling procedures.

Rexar Technical Compound Datasheet (PDF)

Safety Data Sheet (SDS)

Additional public reference

Molecular structure data and selected physicochemical properties can be consulted via: SLU-PP-332 on PubChem

Comprehensive structural overview

SLU-PP-332 is an organic aromatic hydrazone compound with the molecular formula C18H14N2O2 and a molecular weight of approximately 290.3 g/mol. Its molecular architecture contains a hydroxy-substituted benzoyl region connected through a hydrazone linkage to a naphthalene-derived aromatic system.

The structure contains two nitrogen atoms and two oxygen atoms distributed across a hydrazone-hydrazide environment, a carbonyl group and a phenolic hydroxyl group. The combination of two extended aromatic regions, carbonyl functionality, phenolic substitution and nitrogen-containing connectivity provides multiple analytical markers suitable for chromatographic, mass-spectrometric and spectroscopic characterisation.

Naphthalene ring architecture

A defining structural feature of SLU-PP-332 is the presence of a naphthalene ring system. This fused bicyclic aromatic region consists of two condensed benzene rings and represents a substantial portion of the molecule's conjugated aromatic surface.

The naphthalene system provides multiple chemically distinguishable aromatic proton and carbon environments and may contribute strongly to ultraviolet absorption, chromatographic retention and spectroscopic behaviour.

Hydroxybenzoyl-derived region

SLU-PP-332 contains a hydroxy-substituted benzoyl region associated with the hydrazide portion of the molecule. This aromatic component combines a phenyl ring with a phenolic hydroxyl substituent and a carbonyl-containing hydrazide functionality.

The combination of these groups provides characteristic aromatic, carbonyl and hydroxyl environments that can support comparative identification using chromatographic and spectroscopic techniques.

Hydrazone architecture

The molecular framework of SLU-PP-332 contains a hydrazone-type linkage connecting the benzohydrazide region to the naphthalene-derived portion of the molecule.

This nitrogen-containing connectivity introduces chemically distinct nitrogen environments and a carbon-nitrogen double-bond region that can provide useful structural markers during NMR, infrared and mass-spectrometric analysis.

Functional group composition

The molecular formula C18H14N2O2 reflects a structure containing carbon, hydrogen, nitrogen and oxygen distributed across several chemically distinct structural regions.

  • One fused naphthalene ring system
  • One hydroxy-substituted phenyl ring
  • One hydrazone linkage
  • One carbonyl-containing hydrazide region
  • One phenolic hydroxyl group
  • Two nitrogen atoms
  • Two oxygen atoms
  • Multiple conjugated aromatic environments

The combination of aromatic, phenolic, carbonyl and nitrogen-containing structural elements provides multiple analytical markers for comparative compound identification.

Phenolic hydroxyl functionality

SLU-PP-332 contains a phenolic hydroxyl group attached to the benzene-derived aromatic region. This functionality introduces a polar O-H environment into an otherwise extensively aromatic molecular framework.

The phenolic hydroxyl group may contribute characteristic infrared absorption and proton NMR behaviour and can influence solvent interactions, intermolecular association and chromatographic characteristics.

Carbonyl functionality

The benzohydrazide-derived region contains a carbonyl group positioned adjacent to the nitrogen-containing hydrazide functionality.

This carbonyl environment provides a characteristic structural marker that may be observed through infrared spectroscopy and carbon NMR and may also influence molecular polarity and intermolecular interactions.

Nitrogen-containing environments

SLU-PP-332 contains two nitrogen atoms within its hydrazone-hydrazide structural region. These nitrogen atoms occupy chemically distinct environments associated with the carbonyl-containing hydrazide functionality and the carbon-nitrogen double-bond system.

The nitrogen-containing region contributes to the molecular polarity and may influence ionisation behaviour and spectroscopic characteristics under different analytical conditions.

Aromatic ring balance

The molecule contains two principal aromatic regions: a substituted phenyl ring and an extended fused naphthalene system. These aromatic components are connected through the hydrazone-hydrazide framework.

This arrangement creates multiple aromatic proton and carbon environments that can assist structural verification through NMR, ultraviolet spectroscopy and chromatographic comparison.

Conjugated molecular architecture

SLU-PP-332 contains an extended arrangement of aromatic and unsaturated structural elements. The naphthalene system, substituted phenyl ring and hydrazone region collectively contribute to the conjugated character of the molecule.

This conjugation can influence ultraviolet-visible absorption characteristics and provides an analytically useful structural feature for comparative spectroscopic examination.

Heteroatom environments

SLU-PP-332 contains two nitrogen atoms and two oxygen atoms distributed across the hydrazone, carbonyl and phenolic regions of the molecule.

One oxygen atom is present within the carbonyl functionality and the second is present as the phenolic hydroxyl group. The two nitrogen atoms form the central hydrazone-hydrazide connectivity between the aromatic regions.

Hydrogen-bonding characteristics

The phenolic hydroxyl group and hydrazide-associated nitrogen environment provide potential hydrogen-bond donor sites, while the carbonyl oxygen and selected nitrogen environments may contribute hydrogen-bond acceptor character.

This combination can influence solvent interactions, chromatographic behaviour, solid-state organisation and sample-preparation characteristics.

Molecular polarity and hydrophobic balance

SLU-PP-332 combines a substantial aromatic surface area with polar hydroxyl, carbonyl and nitrogen-containing functionalities. This creates a mixed molecular character involving both hydrophobic aromatic regions and more polar functional groups.

This balance is relevant when evaluating solvent selection, sample preparation and reversed-phase chromatographic conditions.

Geometric characteristics

The registered structure of SLU-PP-332 contains defined geometry associated with the hydrazone carbon-nitrogen double bond. This geometric configuration forms part of the registered chemical identity of the compound.

Geometric identity may be relevant during structural characterisation and comparison with authenticated reference material, particularly when spectroscopic techniques are used to distinguish alternative configurations.

Conformational characteristics

The fused naphthalene ring and phenyl ring provide relatively rigid aromatic regions, while the connecting hydrazone-hydrazide functionality permits a more limited range of conformational arrangements.

The combination of rigid aromatic regions and heteroatom-containing connectivity may influence molecular planarity, intermolecular interactions and chromatographic behaviour.

Chromatographic behaviour

Under reversed-phase liquid chromatographic conditions, retention may be influenced by the extensive naphthalene and phenyl aromatic surface area together with the phenolic hydroxyl, carbonyl and nitrogen-containing functionalities.

Retention time and peak shape may vary according to mobile-phase composition, gradient conditions, stationary-phase chemistry, temperature, pH and sample concentration.

Liquid chromatography considerations

LC-based methods may be used for qualitative identity comparison, purity profiling and retention-time verification of SLU-PP-332 reference material.

The combination of extended aromatic surface area and several polar functional groups may require optimisation of mobile-phase composition and stationary-phase chemistry for suitable retention and peak symmetry.

Mass spectrometric considerations

With a molecular weight of approximately 290.3 g/mol, SLU-PP-332 falls within a mass range suitable for routine LC-MS analysis. Appropriate ionisation conditions may support detection of protonated, deprotonated or adduct-associated molecular species depending on solvent composition and instrument parameters.

Fragmentation may involve the hydrazone linkage, benzohydrazide region or naphthalene-associated portion of the molecule and may support structural confirmation when compared with authenticated reference data.

NMR spectroscopic considerations

Proton NMR analysis may show characteristic resonances associated with the naphthalene ring system, substituted phenyl ring, hydrazone-associated proton environment, phenolic hydroxyl group and nitrogen-associated proton environments.

Carbon NMR analysis may provide distinguishable signals corresponding to naphthalene carbons, substituted phenyl carbons, the hydrazone-associated carbon environment and the carbonyl carbon.

Infrared spectroscopic considerations

Infrared analysis may reveal characteristic absorption features associated with the carbonyl group, phenolic O-H environment, nitrogen-associated N-H environment, carbon-nitrogen bonding and aromatic C-H bonds.

The combination of carbonyl, hydroxyl and nitrogen-containing functionalities provides several potentially useful infrared markers for comparative structural characterisation.

Ultraviolet detection considerations

The extended aromatic and conjugated systems of SLU-PP-332 may support ultraviolet-based chromatographic detection. Suitable detection wavelengths should be selected according to measured absorbance characteristics and validated laboratory methods.

The fused naphthalene system and substituted aromatic ring are expected to contribute substantially to the electronic absorption profile of the compound.

Naphthalene chromophore considerations

The naphthalene ring represents a major aromatic chromophore within SLU-PP-332. Its fused bicyclic architecture provides an extended conjugated electronic system that can produce characteristic ultraviolet absorption and spectroscopic behaviour.

Combined with the substituted phenyl ring and hydrazone region, the naphthalene system provides multiple optical and structural markers for comparative analytical identification.

Hydrazone chromophore characteristics

The carbon-nitrogen double-bond region within the hydrazone functionality contributes to the conjugated molecular architecture of SLU-PP-332.

Its electronic relationship with the adjacent aromatic systems may influence absorption characteristics and provide an additional structural marker for spectroscopic comparison.

Carbonyl environment characteristics

SLU-PP-332 contains a single carbonyl group within the benzohydrazide-derived portion of the molecule. This carbonyl occupies a chemically distinct environment adjacent to nitrogen-containing functionality.

Its vibrational and NMR characteristics may provide useful analytical markers for comparison with authenticated reference data.

Phenolic region characteristics

The hydroxy-substituted phenyl region contains an aromatic hydroxyl functionality positioned on the benzohydrazide-derived ring system.

This structural feature provides an additional polar environment and can contribute characteristic proton NMR and infrared features while influencing intermolecular hydrogen bonding.

Solid-state considerations

SLU-PP-332 is supplied as a laboratory solid. Solid-state characteristics such as crystallinity, particle morphology, residual moisture and residual solvent content may depend on manufacturing and purification procedures.

Analytical laboratories may use thermal behaviour, powder analysis or spectroscopic comparison as supplementary identity indicators where appropriate.

Chemical identity and registry metadata

  • Product name: SLU-PP-332
  • Chemical name: 4-hydroxy-N'-[(E)-naphthalen-2-ylmethylidene]benzohydrazide
  • CAS number: 303760-60-3
  • PubChem CID: 5338394
  • Molecular formula: C18H14N2O2
  • Molecular weight: 290.3 g/mol
  • Material form: Laboratory solid

Analytical laboratory applications

SLU-PP-332 may serve as a qualitative reference compound in structural verification and comparative analytical workflows involving LC-MS, HPLC, NMR, ultraviolet detection and infrared spectroscopy. Laboratory procedures may include retention-time comparison, molecular-weight confirmation and comparative spectral profiling.

  • LC-MS molecular-weight verification
  • HPLC retention-time comparison
  • NMR structural analysis
  • Infrared functional-group confirmation
  • Ultraviolet spectroscopic comparison
  • Comparative profiling of hydrazone-containing compounds
  • Comparative analysis of naphthalene-containing reference materials
  • Analytical method development and validation support

Structural classification

SLU-PP-332 can be structurally classified as an aromatic benzohydrazide-derived hydrazone compound containing a fused naphthalene ring system, a hydroxy-substituted phenyl ring and nitrogen-containing carbonyl connectivity.

Its molecular framework provides a distinctive mixed aromatic-hydrazone architecture for comparative analytical workflows involving hydrazones, substituted benzohydrazides, naphthalene-containing compounds and structurally related reference materials.

Naphthalene substitution pattern

The naphthalene region is connected to the central hydrazone functionality through a methylidene-derived carbon environment. This arrangement forms one of the principal structural features distinguishing SLU-PP-332 from simpler benzohydrazide derivatives.

The multiple naphthalene proton and carbon environments provide useful structural markers for NMR and ultraviolet-based analytical comparison.

Phenyl substitution pattern

The second aromatic region consists of a hydroxy-substituted phenyl ring associated with the benzohydrazide portion of the molecule.

This arrangement creates a chemically distinct aromatic environment separate from the naphthalene system and provides additional proton and carbon resonances useful for structural verification.

Hydrazone connectivity

The central portion of SLU-PP-332 contains a sequence of carbonyl, nitrogen and carbon-nitrogen double-bond environments characteristic of hydrazone-containing benzohydrazide structures.

This organisation provides distinctive heteroatom and unsaturated environments that may be evaluated using LC-MS, NMR and infrared analytical methods.

Ionisation behaviour

The phenolic hydroxyl group, hydrazone-hydrazide nitrogen environments and carbonyl functionality may influence ionisation behaviour under different analytical conditions. Protonation, deprotonation and adduct formation may depend on solvent composition, mobile-phase additives and ionisation parameters.

Instrument settings and sample-preparation conditions should therefore be optimised according to validated laboratory procedures.

Elemental composition distribution

The molecular formula C18H14N2O2 contains two nitrogen atoms within the central hydrazone-hydrazide region and two oxygen atoms distributed between the carbonyl and phenolic hydroxyl functionalities.

The theoretical elemental composition can support identity verification when combined with accurate-mass spectrometry and appropriate spectroscopic or elemental analysis.

Reference positioning in analytical workflows

As a chemical reference material, SLU-PP-332 may be used for qualitative structural comparison, method development and analytical identity verification in laboratories examining hydrazones, aromatic hydrazides, naphthalene-containing compounds or structurally related reference materials.

Analytical reproducibility depends on consistent sample preparation, validated instrument parameters, suitable reference documentation and controlled storage conditions.

Material consistency and traceability

Each unit is supplied in sealed laboratory packaging designed to support material integrity during storage and transport. Batch identification labelling supports traceability and internal documentation within controlled research environments.

Packaging should remain closed when the material is not in use and should be protected from moisture, excessive heat and direct light.

Handling and storage conditions

  • Storage: Store according to the conditions stated in the accompanying product documentation.
  • Handling: Handle according to standard laboratory safety procedures and the accompanying safety documentation.
  • Personal protection: Use appropriate laboratory gloves, protective clothing and eye protection.
  • Moisture protection: Minimise unnecessary exposure to air and humidity.
  • Long-term storage: Follow the conditions stated in the product documentation and applicable laboratory procedures.

 

Frequently asked technical questions

What is the CAS number of SLU-PP-332?
The CAS number is 303760-60-3.

What is the PubChem CID of SLU-PP-332?
The PubChem compound identifier is 5338394.

What is the molecular formula of SLU-PP-332?
The molecular formula is C18H14N2O2.

What is the molecular weight of SLU-PP-332?
The molecular weight is approximately 290.3 g/mol.

What is the chemical name of SLU-PP-332?
A recognised chemical name is 4-hydroxy-N'-[(E)-naphthalen-2-ylmethylidene]benzohydrazide.

What structural class does SLU-PP-332 belong to?
SLU-PP-332 is an aromatic hydrazone compound containing benzohydrazide, phenolic and naphthalene structural regions.

How many nitrogen atoms does SLU-PP-332 contain?
The molecular structure contains two nitrogen atoms.

How many oxygen atoms does SLU-PP-332 contain?
The molecular structure contains two oxygen atoms.

Does SLU-PP-332 contain a defined geometric configuration?
Yes. The registered structure contains defined geometry associated with the hydrazone carbon-nitrogen double bond.

In which form is SLU-PP-332 supplied?
It is supplied as a laboratory solid in sealed packaging.

Is this product intended for human or animal use?
No. This material is supplied exclusively as a laboratory reference compound.

Disclaimer:
This product is supplied exclusively as a chemical reference material for laboratory and analytical purposes. Not for human or animal consumption. Not intended for food, supplement, cosmetic, medical, diagnostic or therapeutic use.

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Specifications

Intended use: Laboratory research and analytical reference purposes only
Application area: Analytical chemistry, reference comparison and method development
End user: Professional users in controlled research environments
Regulatory classification: Chemical reference material
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