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Agmatine Sulfate is supplied by Rexar as a chemical reference material for analytical chemistry, compound identification and laboratory-based comparison workflows. This material is intended for controlled research environments requiring verified chemical identity and consistent reference-grade specifications.
Agmatine Sulfate (CAS 2482-00-0) is available directly through the Rexar webshop and supplied in sealed laboratory packaging for distribution within the EU.
Rexar Technical Compound Datasheet (PDF)
Agmatine Sulfate | CAS: 2482-00-0 | Molecular formula: C5H16N4O4S | Molecular weight: 228.27 g/mol.
Agmatine sulfate is the sulfate salt form of agmatine, a decarboxylated derivative of the amino acid L-arginine. Structurally, agmatine contains a primary amine group linked via a four-carbon aliphatic chain to a guanidine functional group. In the sulfate form, protonated agmatine cations are associated with sulfate anions through ionic interactions.
The guanidine moiety is strongly basic due to resonance stabilisation of the cationic form. This contributes to high aqueous solubility and defined protonation behaviour under laboratory conditions.
Agmatine sulfate is supplied as the sulfate salt rather than the free base. The presence of sulfuric acid results in protonated amine groups forming ionic associations with sulfate anions.
The salt form influences:
Unless otherwise specified, all analytical data on this page refers specifically to the sulfate salt form (CAS 2482-00-0).
The molecular structure contains:
The guanidine group exhibits strong basicity and can participate in hydrogen bonding and electrostatic interactions. This influences chromatographic behaviour and solubility characteristics.
Agmatine belongs structurally to the broader class of polyamine-related compounds. Within chemical registries, it is classified as a guanidine-containing biogenic amine derivative.
The sulfate salt form provides enhanced stability and defined stoichiometry suitable for analytical reference purposes.
Agmatine sulfate is typically encountered as a white crystalline powder. As an ionic compound, it demonstrates high water solubility and defined dissociation behaviour in aqueous media.
Physicochemical evaluation may include:
In proton NMR, aliphatic methylene groups generate characteristic signals in the upfield region. The guanidine protons may display broadened signals due to exchange effects in aqueous solvents.
Infrared spectroscopy typically reveals strong sulfate stretching bands in addition to amine-related absorptions.
Due to its polar and ionic nature, agmatine sulfate may exhibit limited retention in standard reversed-phase systems without ion-pairing agents. Method development may require adjustment of mobile phase composition or use of hydrophilic interaction chromatography (HILIC).
Retention time comparison and peak symmetry evaluation are commonly applied in reference workflows.
Sulfur content corresponding to the sulfate anion may be verified through elemental analysis or ICP-based techniques. Nitrogen content confirms integrity of the guanidine structure.
Such analyses support verification of correct salt stoichiometry.
Under recommended storage conditions, agmatine sulfate is chemically stable. Prolonged exposure to elevated humidity may influence moisture uptake due to its ionic nature.
Storage in a dry environment between 8–20 °C supports long-term stability.
Is this the free base form?
No. This product is supplied as the sulfate salt.
Does the sulfate influence molecular weight?
Yes. The molecular weight listed reflects the sulfate salt composition.
Is agmatine sulfate hygroscopic?
Ionic salts may exhibit moisture sensitivity. Dry storage conditions are recommended.
Can sulfur content be analytically confirmed?
Yes. Sulfur may be quantified using elemental analysis or ICP-based methods.
Agmatine Sulfate may be used as a qualitative reference material in analytical workflows, including retention time comparison, spectral confirmation and compositional verification under standard laboratory conditions.
Molecular structure data and selected physicochemical properties can be consulted via the public database: Agmatine Sulfate on PubChem .
Agmatine contains both a primary amine and a guanidine functional group. The guanidine moiety exhibits strong basicity due to resonance stabilisation of its protonated form. In the sulfate salt, protonated agmatine species are electrostatically associated with sulfate anions.
The protonation state may influence solubility, chromatographic retention and spectral behaviour. Under aqueous conditions, dissociation of the sulfate salt yields agmatinium cations and sulfate anions.
The molecular formula reflects a defined salt stoichiometry. Ionic balance between the positively charged agmatine species and the divalent sulfate anion ensures charge neutrality in solid form.
Verification of sulfate presence may be performed via elemental sulfur analysis or sulfate-specific detection methods.
Upon dissolution in water, agmatine sulfate dissociates into its ionic components. The degree of dissociation is influenced by concentration and ionic strength of the medium.
In buffered analytical systems, control of pH is important to maintain reproducible retention and peak shape.
As an organic sulfate salt, thermal exposure may lead to decomposition rather than a defined melting transition. Thermal analysis can provide insight into dehydration or breakdown processes.
Such evaluation may be relevant in quality control environments requiring stability assessment.
Agmatine may also exist in free base form; however, the sulfate salt typically exhibits improved handling characteristics, defined stoichiometry and enhanced stability under storage conditions.
Analytical parameters such as molecular weight, solubility and hygroscopicity differ between salt and free base forms.
Highly polar guanidine-containing compounds may exhibit limited retention in standard reversed-phase HPLC systems. Alternative techniques such as HILIC or ion-pair chromatography may improve retention and separation.
Method development may include optimisation of mobile phase composition, ionic strength and detection wavelength.
In chemical databases, agmatine sulfate is indexed under guanidine derivatives, biogenic amines and sulfate salts. Registry metadata typically includes SMILES strings, InChI identifiers and structural diagrams supporting compound verification.
Does agmatine sulfate contain a guanidine functional group?
Yes. The guanidine moiety is a defining structural feature.
Is the sulfate anion analytically detectable?
Yes. Sulfate can be confirmed through elemental sulfur analysis or ion chromatography.
Does the salt form affect chromatographic retention?
Yes. Ionic interactions influence retention behaviour in various chromatographic systems.
What is the CAS number of Agmatine Sulfate?
The CAS number of Agmatine Sulfate is 2482-00-0.
In which form is Agmatine Sulfate supplied?
This product is supplied as a white crystalline powder in sealed laboratory packaging.
Is this product intended for human or animal use?
No. This material is supplied exclusively as a laboratory reference compound.
Is Agmatine Sulfate available for shipment within the EU?
Yes. Orders are supplied through the Rexar webshop in sealed laboratory packaging.
Disclaimer:
This product is intended for laboratory research use only. It is not intended for human or animal consumption, nor for medical, diagnostic, or therapeutic applications.
| Intended use: | Laboratory research and analytical reference purposes only |
| Application area: | Analytical chemistry, reference comparison and method development |
| End user: | Professional users in controlled research environments |
| Regulatory classification: | Chemical reference material |
