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Indolepropionamide (IPAM) is supplied by Rexar as a research-grade chemical reference material for analytical chemistry, compound identification and laboratory comparison workflows. Chemically identified as 3-(1H-indol-3-yl)propanamide, this indole-containing compound combines an aromatic heterocyclic indole framework with a propanamide side chain and is provided exclusively for controlled research environments requiring verified chemical identity, consistent structural documentation and reproducible analytical comparison.
Research-grade material distributed by Rexar within the European Union.
Indolepropionamide (IPAM) (CAS 5814-93-7) is supplied in sealed laboratory packaging to support traceability, storage integrity and laboratory handling procedures.
Rexar Technical Compound Datasheet (PDF)
Molecular structure data and selected physicochemical properties can be consulted via: Indolepropionamide (IPAM) on PubChem
Indolepropionamide (IPAM) is an indole-containing organic compound with the molecular formula C11H12N2O. Its molecular architecture consists of an indole ring system connected at the 3-position to a three-carbon propanamide side chain.
The structure contains two nitrogen atoms and one oxygen atom distributed between the indole heterocycle and terminal amide functionality. The aromatic heterocyclic framework, flexible alkyl linker and amide group provide distinctive structural features suitable for chromatographic, mass-spectrometric and spectroscopic characterisation.
A defining structural element of Indolepropionamide is its indole core. The indole system consists of a benzene ring fused to a five-membered nitrogen-containing pyrrole ring, creating a compact bicyclic aromatic heterocycle.
This fused aromatic architecture provides a relatively rigid conjugated region and several characteristic structural markers that may support comparative analytical identification.
At the 3-position of the indole system, IPAM contains a propanamide side chain consisting of a short aliphatic linker terminating in a primary amide functionality.
This side chain introduces conformational flexibility outside the rigid indole framework and creates a chemically distinct polar region that may influence chromatographic retention, solubility and spectroscopic behaviour.
The molecular formula C11H12N2O reflects a structure containing carbon, hydrogen, nitrogen and oxygen distributed across several chemically distinct structural regions.
The combination of aromatic, heterocyclic, aliphatic and amide structural elements provides multiple analytical markers for comparative compound identification.
Indolepropionamide contains a terminal primary amide group. This functionality includes one carbonyl group and one nitrogen atom and contributes significantly to the local polarity of the molecule.
The amide carbonyl may produce a characteristic infrared absorption feature and a distinguishable carbon resonance during carbon NMR analysis, while the amide nitrogen may participate in hydrogen-bonding interactions.
One nitrogen atom is incorporated directly into the five-membered portion of the indole system. This pyrrolic nitrogen forms part of the aromatic heterocyclic framework and contributes to the electronic characteristics of the fused ring system.
The indole nitrogen may influence hydrogen bonding, chromatographic behaviour and spectroscopic response under different analytical conditions.
The indole core contains a fused aromatic system consisting of a benzene region and a nitrogen-containing five-membered ring. This conjugated framework creates multiple aromatic proton and carbon environments.
These aromatic regions may provide characteristic NMR signals and support ultraviolet absorbance associated with the conjugated indole chromophore.
The propanamide side chain contains an aliphatic carbon segment linking the indole ring to the terminal amide group. This flexible region separates the aromatic core from the polar amide functionality.
The aliphatic methylene environments may provide distinguishable proton and carbon NMR resonances and contribute to conformational flexibility within the molecule.
Indolepropionamide contains both an indole nitrogen and a primary amide group that may participate in intermolecular hydrogen-bonding interactions under analytical and solid-state conditions.
The carbonyl oxygen provides a hydrogen-bond acceptor environment, while nitrogen-associated hydrogen atoms may act as hydrogen-bond donors. These interactions may influence solvation, crystal packing and chromatographic behaviour.
The molecule combines a hydrophobic aromatic indole region with a polar amide functionality connected through a short aliphatic linker. This produces a mixed structural character involving both aromatic hydrophobicity and localised polarity.
This balance is relevant when evaluating solvent selection, sample preparation and reversed-phase chromatographic conditions.
The fused indole system provides a relatively rigid aromatic framework, while the propanamide side chain introduces rotational flexibility through several carbon-carbon bonds.
No defined stereogenic centre is present in the standard molecular representation, and the compound is represented without specified stereochemistry.
Under reversed-phase liquid chromatographic conditions, retention may be influenced by the aromatic indole framework, the polar amide functionality, the aliphatic linker and the overall balance between hydrophobic and polar structural regions.
Retention time and peak shape may vary according to mobile-phase composition, gradient conditions, stationary-phase chemistry, temperature and sample concentration.
LC-based methods may be used for qualitative identity comparison, purity profiling and retention-time verification of Indolepropionamide reference material.
The combination of an aromatic indole system and a polar amide group may require optimisation of mobile-phase composition and stationary-phase chemistry to obtain suitable retention and peak symmetry.
With a molecular weight of approximately 188.23 g/mol, Indolepropionamide falls within a mass range suitable for routine LC-MS analysis. Appropriate ionisation techniques may support detection of protonated, deprotonated or adducted molecular species depending on solvent composition, mobile-phase conditions and instrument parameters.
Fragmentation may involve the indole system, the aliphatic linker or the amide-containing region and can support structural confirmation when compared with authenticated reference data.
Proton NMR analysis may show characteristic resonances associated with aromatic protons of the indole system together with signals originating from the aliphatic methylene groups and exchangeable nitrogen-associated protons.
Carbon NMR analysis may provide distinguishable signals corresponding to aromatic and heterocyclic carbons, aliphatic linker carbons and the amide carbonyl carbon.
Infrared analysis may reveal characteristic absorption features associated with the amide carbonyl, N-H environments, aromatic C-H bonds and aliphatic C-H bonds.
The amide carbonyl may provide a prominent absorption feature that can assist structural comparison when evaluated against an authenticated reference spectrum.
The conjugated indole ring system may support ultraviolet-based chromatographic detection. Suitable detection wavelengths should be selected according to measured absorbance characteristics and validated laboratory methods.
The fused aromatic heterocyclic framework is expected to contribute substantially to the electronic absorption profile of the compound.
The indole system represents the primary conjugated chromophore within Indolepropionamide. Its fused aromatic architecture may produce characteristic ultraviolet absorbance and fluorescence-related behaviour under appropriate analytical conditions.
These optical characteristics may provide additional analytical markers during structural comparison and compound identification.
Indolepropionamide is supplied as a laboratory powder. Solid-state characteristics such as crystallinity, particle morphology, residual moisture and residual solvent content may depend on manufacturing and purification procedures.
Analytical laboratories may use melting behaviour, powder analysis or spectroscopic comparison as supplementary identity indicators where appropriate.
Indolepropionamide may serve as a qualitative reference compound in structural verification and comparative analytical workflows involving LC-MS, HPLC, NMR and infrared spectroscopy. Laboratory procedures may include retention-time comparison, molecular-weight confirmation and comparative spectral profiling.
Indolepropionamide can be structurally classified as an indole-containing amide compound comprising a fused aromatic nitrogen heterocycle connected to a terminal propanamide group.
Its molecular framework differs from fused multi-nitrogen heterocycles, racetams and phenibut-related structures and provides a distinct indole-amide architecture for comparative analytical workflows.
The indole framework of IPAM consists of a benzene ring fused to a five-membered nitrogen-containing heterocycle. This fused structure forms a compact and conjugated aromatic molecular region.
The fused indole architecture may produce characteristic chromatographic retention, ultraviolet absorbance and NMR signals useful for analytical comparison.
The molecular structure contains a propanamide chain attached to the 3-position of the indole framework. This substitution pattern provides a defined structural relationship between the aromatic core and the terminal polar functional group.
The methylene groups within the side chain may provide useful spectroscopic markers during structural verification.
The two nitrogen atoms in Indolepropionamide occupy chemically distinct environments. One forms part of the aromatic indole heterocycle, while the second is incorporated into the primary amide group.
These distinct nitrogen environments contribute to the electronic, hydrogen-bonding and spectroscopic characteristics of the molecule.
Indolepropionamide contains one carbonyl functionality within its terminal amide group. This carbonyl environment contributes to molecular polarity and provides a distinct spectroscopic marker.
The carbonyl carbon may provide a characteristic carbon NMR resonance, while its vibrational behaviour may produce a prominent infrared absorption feature.
The indole nitrogen and amide functionality may influence ionisation behaviour under different analytical conditions.
Mobile-phase composition, solvent system and ionisation parameters can therefore affect mass-spectrometric response and chromatographic behaviour.
The molecular formula C11H12N2O contains one nitrogen atom within the indole heterocycle, one nitrogen atom within the amide functionality and one oxygen atom associated with the amide carbonyl.
Theoretical elemental composition may support identity verification when combined with mass spectrometry and spectroscopic analysis.
As a chemical reference material, Indolepropionamide may be used for qualitative structural comparison, method development and analytical identity verification in laboratories examining indole derivatives, aromatic amides or related heterocyclic reference materials.
Analytical reproducibility depends on consistent sample preparation, validated instrument parameters, suitable reference documentation and controlled storage conditions.
Each unit is supplied in sealed laboratory packaging designed to support material integrity during storage and transport. Batch identification labelling supports traceability and internal documentation within controlled research environments.
Packaging should remain closed when the material is not in use and should be protected from moisture, excessive heat and direct light.
What is the CAS number of Indolepropionamide (IPAM)?
The CAS number is 5814-93-7.
What is the PubChem CID of Indolepropionamide?
The PubChem compound identifier is 351791.
What is the molecular formula of Indolepropionamide?
The molecular formula is C11H12N2O.
What is the molecular weight of Indolepropionamide?
The molecular weight is approximately 188.23 g/mol.
What is the chemical name of Indolepropionamide?
The chemical name is 3-(1H-indol-3-yl)propanamide.
What structural class does Indolepropionamide belong to?
Indolepropionamide is an indole-containing amide compound combining a fused aromatic heterocycle with a propanamide side chain.
How many nitrogen atoms does Indolepropionamide contain?
The molecular structure contains two nitrogen atoms.
How many oxygen atoms does Indolepropionamide contain?
The molecular structure contains one oxygen atom associated with the amide carbonyl functionality.
In which form is Indolepropionamide supplied?
It is supplied as a laboratory powder in sealed packaging.
Is this product intended for human or animal use?
No. This material is supplied exclusively as a laboratory reference compound.
Disclaimer:
This product is supplied exclusively as a chemical reference material for laboratory and analytical purposes. Not for human or animal consumption. Not intended for food, supplement, cosmetic, medical, diagnostic or therapeutic use.
| Intended use: | Laboratory research and analytical reference purposes only |
| Application area: | Analytical chemistry, reference comparison and method development |
| End user: | Professional users in controlled research environments |
| Regulatory classification: | Chemical reference material |
